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Even if susceptibility to oxaliplatin-induced peripheral neurotoxicity has been noted in various mouse strains, the difficulty in the identification of reliable predictors of high-risk subjects for its development and the largely incomplete knowledge of the basic mechanisms of drug-induced toxic effects on the peripheral nervous system components are critical [48]

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Pre-emptive short-term nicotinamide mononucleotide treatment in a mouse model of diabetic nephropathy